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topologyGSA (version 1.4.5)

Gene Set Analysis Exploiting Pathway Topology

Description

Using Gaussian graphical models we propose a novel approach to perform pathway analysis using gene expression. Given the structure of a graph (a pathway) we introduce two statistical tests to compare the mean and the concentration matrices between two groups. Specifically, these tests can be performed on the graph and on its connected components (cliques).

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Install

install.packages('topologyGSA')

Monthly Downloads

356

Version

1.4.5

License

GPL-3

Maintainer

Last Published

July 9th, 2015

Functions in topologyGSA (1.4.5)