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drc (version 2.0-1)

Analysis of dose-response curves

Description

Analysis of one or multiple curves with focus on concentration-response, dose-response and time-response curves used, for example in biology, environmental sciences, medicine, pharmacology, toxicology.

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Version

Install

install.packages('drc')

Monthly Downloads

28,339

Version

2.0-1

License

GPL (>= 2)

Homepage

http://www.r-project.org

Maintainer

Christian Ritz

Last Published

September 23rd, 2010

Functions in drc (2.0-1)

The four-parameter log-logistic function

Mortality of tobacco budworms

Expected or predicted response

Michaelis-Menten model

Comparing selectivity indices across curves

The two-parameter Weibull functions

Maximum mean response

The Cedergreen-Ritz-Streibig model

Transform-both-sides Box-Cox transformation

The three-parameter Weibull functions

Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis

Effect of technical grade and commercially formulated auxin herbicides

Deguelin applied to chrysanthemum aphis

The three-parameter log-logistic function

The Brain-Cousens hormesis models

Volume of algae as function of increasing concentrations of a herbicide

Acifluorfen and diquat tested on Lemna minor.

getMeanFunctions

Display available dose-response models

Example from Finney (1971)

The Brain-Cousens hormesis models

The two-parameter log-logistic function

Example of plant growth curve from Covarelli and Onofri (1998)

Estimating effective doses

Fitting dose-response models

Comparison of effective dose values

Root length measurements

The Cedergreen-Ritz-Streibig model

The log-logistic function

Extract Model Coefficients

Gompertz growth models

Competition between two biotypes

Effect of sodium pentachlorophenate on growth of fathead minnow

The modified baro5 function

Vinclozolin from AR in vitro assay

ANOVA for dose-response model fits

Extract fitted values from model

Creating isobolograms

Information on estimation

Heart rate baroreflexes for rabbits

Earthworm toxicity test

Bayesian Information Criterion for dose-response models

The five-parameter log-logistic function

Fitting mixture models

Dose-response profile of degradation of agrochemical using lepidium

S.capricornutum

Effect of cadmium on growth of green alga

Extracting the log likelihood

Showing starting values used

Effect of ferulic acid on growth of ryegrass

Model-robust dose-response modelling

Searching through a range of initial parameter values to obtain convergence

Test data from a 21 day fish test

Model selection

Log-normal dose-response model

Sets control arguments

Summarising non-linear model fits

Checking the model fot

The logistic model

Potency of two herbicides

Dose-response model for estimation of no effect concentration (NEC).

Mizon-Richard test for dose-response models

The four-parameter Weibull functions

Exponential decay model

Estimation of ED values using model-averaging

Two-phase dose-response model

Extracting residuals from model

Herbicide applied to Galium aparine

Mechlorprop and terbythylazine tested on Lemna minor

The effect of terbuthylazin on growth rate

The derivative of the Gompertz function

Neill's lack-of-fit test for dose-response models

Fractional polynomial-logistic dose-response models

Printing key features

Isobutylalcohol in nutrient solution in which lettuce plants were grown

Plotting fitted curves for a 'drc' or 'mrdrc' object

print.summary.drc

Printing summary of non-linear model fits

Calculating yield loss parameters

Comparison of parameters

Bread and meat for the sandwich

Asymptotic regression model

Effect of erythromycin on mixed sewage microorganisms

Effect of an effluent on the growth of mysid shrimp

Confidence Intervals for model parameters

Weight gain for different methionine sources

Inhibition of photosynthesis

Simulating ED values under various scenarios

Calculating variance-covariance matrix for objects of class 'drc'

Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction

Weibull model functions

Updating and re-fitting a model

Mean function for the Gompertz dose-response or growth curve

Simulating a dose-response curve

Leaf length of barley

Glyphosate and metsulfuron-methyl tested on algae.

Lack-of-fit test for the mean structure based on cumulated residuals

Dose-response profile of degradation of agrochemical using nasturtium