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BEAMR

The BEAMR package implements the Bootstrap Evaluation of Association Matrices (BEAM) method to identify genes that have multiple genomic features associated with multiple clinical endpoints. It uses simple association models and bootstraping to integrate multiple genomic features.

Installation

You can install BEAMR from CRAN with:

install.packages("BEAMR")

You can install the development version of BEAMR from GitHub with:

# install.packages("devtools")
devtools::install_github("annaSeffernick/BEAMR")

Example

See the vignette at BEAMR Vignette.

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Version

Install

install.packages('BEAMR')

Monthly Downloads

181

Version

1.1.0

License

GPL (>= 3)

Issues

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Maintainer

Anna Eames Seffernick

Last Published

July 27th, 2024

Functions in BEAMR (1.1.0)

get_id_index

For each row of the data.frame main.data, find the index of the matching element in vector ids
print.beam.data

Print summary information about a beam.data object
print.beam.stats

Print summary information about beam.stats object
prep_beam_plot

Prepare for BEAM plotting
prep_beam_specs

Prepare beam.specs
plot_feat_clin

Plot BEAM Feature
prep_beam_data

Prepare data for BEAM analysis
plot_beam_clin

Plot BEAM Sets
plot_beam_boot

Plot bootstrap output for BEAM sets
subset_beam_result

Subset beam.stats Result
specs

Pediatric T-ALL BEAMR Analysis Specs Data from COG trial AALL0434
setdat

Map of Pediatric Data from COG trial AALL0434
beam_dat

Pediatric T-ALL Clinical Data from COG trial AALL0434
check_list_class

Check that each element of a list is of a required class
check_beam_specs

Check that beam.specs satisfies all necessary conditions
clean_Bmtx

Clean up bootstrap coefficient matrix
compute_set_pvalues

Compute BEAMR p-values for sets
gen_beam_plot_list

Generate BEAM Plot List
extend_set_data

Extend set definition data with genes on the same row separated by commas, semicolons, slashes, etc
compute_feature_pvalues

Compute feature level p-values from BEAM statistics
find_id_clm

Find the column of mtch.data with the most rows containing an element of ids
extract_beam_stats

Extract beam stats for a specific set
compute_beam_stats

Compute bootstrap model coefficients for BEAM
clinf

Pediatric T-ALL Clinical Data from COG trial AALL0434
beam_specs_sm

Pediatric T-ALL BEAM Analysis Specs Data from COG trial AALL0434
beam_dat_sm

Pediatric T-ALL Clinical Data from COG trial AALL0434
beam_stats

Pediatric T-ALL Clinical Data from COG trial AALL0434
omicann

Pediatric T-ALL Omics Annotation Data from COG trial AALL0434
beam_stats_sm

Pediatric T-ALL Clinical Data from COG trial AALL0434
beam_specs

Pediatric T-ALL BEAM Analysis Specs Data from COG trial AALL0434
omicdat

Pediatric T-ALL Omics Data from COG trial AALL0434