Statistical tools for the analysis of ChIP-seq data
Description
Statistical tools for ChIP-seq data analysis. The package
includes the statistical method described in Kaufmann et al.
(2009) PLoS Biology: 7(4):e1000090. Briefly, Taking the average
DNA fragment size subjected to sequencing into account, the
software calculates genomic single-nucleotide read-enrichment
values. After normalization, sample and control are compared
using a test based on the Poisson distribution. Test statistic
thresholds to control the false discovery rate are obtained
through random permutation.