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sybilcycleFreeFlux (version 2.0.2)

Cycle-Free Flux Balance Analysis (CycleFreeFlux)

Description

Implement cycle-Free flux balance analysis (CycleFreeFlux), cycle-free flux variability, and Random Sampling of solution space. Desouki, A. A., Jarre, F., Gelius-Dietrich, G., & Lercher, M. J. (2015). CycleFreeFlux: efficient removal of thermodynamically infeasible loops from flux distributions. Bioinformatics, 31(13), 2159-2165. . Flux balance analysis is a technique to find fluxes in metabolic models at steady state. It is described in Orth, J.D., Thiele, I. and Palsson, B.O. What is flux balance analysis? Nat. Biotech. 28, 245-248 (2010).

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Version

Install

install.packages('sybilcycleFreeFlux')

Monthly Downloads

18

Version

2.0.2

License

GPL-3

Maintainer

Abdelmoneim Amer Desouki

Last Published

January 13th, 2021

Functions in sybilcycleFreeFlux (2.0.2)

ACHR

Random Sampling of Solution Space
getModel_WW

based on the algorithm given in Wright & Wagner 2008
llFBA

looplessFBA
enumerateCycles

function to enumerate cycles
iAF1260

Escherichia coli Metabolic Model iAF1260
cfFBA

cycle free flux
iMM904

Saccharomyces cerevisiae Metabolic Model
sybilcycleFreeFlux-package

Find flux distribution free of cycles
cfFVA

cycle free flux variability