Learn R Programming

RNAinteract (version 1.20.0)

Estimate Pairwise Interactions from multidimensional features

Description

RNAinteract estimates genetic interactions from multi-dimensional read-outs like features extracted from images. The screen is assumed to be performed in multi-well plates or similar designs. Starting from a list of features (e.g. cell number, area, fluorescence intensity) per well, genetic interactions are estimated. The packages provides functions for reporting interacting gene pairs, plotting heatmaps and double RNAi plots. An HTML report can be written for quality control and analysis.

Copy Link

Version

Version

1.20.0

License

Artistic-2.0

Maintainer

Bernd Fischer

Last Published

February 15th, 2017

Functions in RNAinteract (1.20.0)

sgisubset

subset of an RNAinteract object.
swaptree

Swaps a branch of a hclust object.
getData

Primary access function for all screen data.
normalizePlateEffect

Normalization of plate effects
embedPCA

Computes a PCA for a pairwise interaction matrix.
sgi

Dataset of class 'RNAinteract'
getScale

get scale information for a channel.
normalizeMainEffectTemplate

normalize template main effect
bindscreens

bind RNAinteract objects along screens
plotHeatmap

plots a heatmap for an interaction screen.
getReplicateData

Extract replicates measurements from the screen.
RNAinteract-class

Class "RNAinteract"
sgisubsetQueryDesign

Subsetting query genes in a RNAinteract object.
getScreenNames

get names of screens and channels
reportAnnotation

Specialized report functions
startReport

start and end a RNAinteract report
createRNAinteractFromFiles

create an RNAinteract object from text files
computePI

compute pairwise interaction
computePValues

compute p-values
estimateMainEffect

estimate main effect
createRNAinteract

create a RNAinteract object
grid.doublePerturbation

Double Perturbation Plot Grob
normalizeMainEffectQuery

normalize query main effect
plotDoublePerturbation

Double Perturbation Plot
getMain

get main effects
RNAinteract-package

Analysis of Pairwise Interaction Screens.
grid.sgiHeatmap

A heatmap grob
summarizeScreens

summarize screens
createCellHTSFromFiles

create cellHTS2 object from text files